kirazmattson
789 posts
Dec 14, 2025
10:00 PM
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Vilitra contains vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction. The dosage is adjusted for age or health because these factors affect how the body metabolizes the drug and how sensitive it is to side effects. Here’s a detailed explanation: Reasons for Dosage Adjustment Age (Elderly Patients) Older adults often have slower metabolism and reduced liver and kidney function, which can increase blood levels of vardenafil. This can lead to more intense side effects such as headache, dizziness, flushing, or low blood pressure. Starting at a lower dose (e.g., 5–10 mg) is common, with gradual adjustment based on tolerance. Liver Impairment Vardenafil is primarily metabolized by the Vilitra liver. Moderate to severe liver disease reduces drug clearance, increasing risk of side effects. Lower starting doses are recommended, and severe cases may require avoidance. Kidney Impairment Reduced kidney function slows elimination of vardenafil. Elderly patients often have some degree of renal impairment, so the dose is often reduced to prevent accumulation and toxicity. Cardiovascular Health Vardenafil can lower blood pressure slightly, which is riskier in men with heart disease, unstable angina, or those on nitrates/alpha-blockers.
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